Publications

2022

Broussard, Gerard, Mikhail Kislin, Caroline Jung, and Samuel S.-H. Wang. “A Flexible Platform for Monitoring Cerebellum-Dependent Sensory Associative Learning..” Journal of visualized experiments : JoVE 179 (2022): n. pag.
Chen, Xiaoying, Yanhua Du, Gerard Broussard, Mikhail Kislin, Carla Yuede, Shuwei Zhang, Sabine Dietmann, Harrison Gabel, Guoyan Zhao, Samuel S.-H. Wang, Xiaoqing Zhang, and Azad Bonni. “Transcriptomic Mapping Uncovers Purkinje Neuron Plasticity Driving Learning..” Nature 605.7911 (2022): 722–727.
Klibaite, Ugne, Mikhail Kislin, Jessica Verpeut, Silke Bergeler, Xiaoting Sun, Joshua Shaevitz, and Samuel S.-H. Wang. “Deep Phenotyping Reveals Movement Phenotypes in Mouse Neurodevelopmental Models..” Molecular autism 13.1 (2022): 12.
Oostland, Marlies, Mikhail Kislin, Yuhang Chen, Tiffany Chen, Sarah Jo Venditto, Ben Deverett, and Samuel S.-H. Wang. “Cerebellar Acceleration of Learning in an Evidence-Accumulation Task.” bioRxiv (2022): n. pag.
Pereira, Talmo, Nathaniel Tabris, Arie Matsliah, David Turner, Junyu Li, Shruthi Ravindranath, Eleni Papadoyannis, Edna Normand, David Deutsch, Yan Wang, Grace McKenzie-Smith, Catalin Mitelut, Marielisa Castro, John D’Uva, Mikhail Kislin, Dan Sanes, Sarah Kocher, Samuel S.-H. Wang, Annegret Falkner, Joshua Shaevitz, and Mala Murthy. “SLEAP: A Deep Learning System for Multi-Animal Pose Tracking..” Nature methods 19.4 (2022): 486–495.
Pisano, Thomas, Austin Hoag, Zahra Dhanerawala, Sara Guariglia, Caroline Jung, Henk-Jan Boele, Kelly Seagraves, Jessica Verpeut, and Samuel S.-H. Wang. “Automated High-Throughput Mouse Transsynaptic Viral Tracing Using IDISCO+ Tissue Clearing, Light-Sheet Microscopy, and BrainPipe..” STAR protocols 3.2 (2022): 101289.
Verpeut, Jessica L., Silke Bergeler, Mikhail Kislin, William Townes, Ugne Klibaite, Zahra M. Dhanerawala, Austin Hoag, Caroline Jung, Junuk Lee, Thomas J. Pisano, Kelly M. Seagraves, Joshua W. Shaevitz, and Samuel S.-H. Wang. “Cerebellar Contributions to a Brainwide Network for Flexible Behavior.” bioRxiv (2022): n. pag.

2021

Pisano, Thomas, Zahra Dhanerawala, Mikhail Kislin, Dariya Bakshinskaya, Esteban Engel, Ethan Hansen, Austin Hoag, Junuk Lee, Nina Oude, Kannan Umadevi Venkataraju, Jessica Verpeut, Freek Hoebeek, Ben Richardson, Henk-Jan Boele, and Samuel S.-H. Wang. “Homologous Organization of Cerebellar Pathways to Sensory, Motor, and Associative Forebrain.” Cell Reports 36.12 (2021): 109721. Print.
Zhang, Yan, Márton Rózsa, Yajie Liang, Daniel Bushey, Ziqiang Wei, Jihong Zheng, Daniel Reep, Gerard Joey Broussard, Arthur Tsang, Getahun Tsegaye, Sujatha Narayan, Christopher J. Obara, Jing-Xuan Lim, Ronak Patel, Rongwei Zhang, Misha B. Ahrens, Glenn C. Turner, Samuel S.-H. Wang, Wyatt L. Korff, Eric R. Schreiter, Karel Svoboda, Jeremy P. Hasseman, Ilya Kolb, and Loren L. Looger. “Fast and Sensitive GCaMP Calcium Indicators for Imaging Neural Populations.” bioRxiv (2021): n. pag.

2019

Deverett, Ben, Mikhail Kislin, David W. Tank, and Samuel S.-H. Wang. “Cerebellar Disruption Impairs Working Memory During Evidence Accumulation.” Nature Communications (2019): n. pag.
Pereira, Talmo, Diego Aldarondo, Lindsay Willmore, Mikhail Kislin, Samuel S.-H. Wang, Mala Murthy, and Joshua Shaevitz. “Fast Animal Pose Estimation Using Deep Neural Networks..” Nature methods 16.1 (2019): 117–125.
Titley, Heather, Mikhail Kislin, Dana Simmons, Samuel S.-H. Wang, and Christian Hansel. “Complex Spike Clusters and False-Positive Rejection in a Cerebellar Supervised Learning Rule..” The Journal of physiology 597.16 (2019): 4387–4406.
Zanin, Juan, Jessica Verpeut, Ying Li, Michael Shiflett, Samuel S.-H. Wang, Viji Santhakumar, and Wilma Friedman. “The p75NTR Influences Cerebellar Circuit Development and Adult Behavior via Regulation of Cell Cycle Duration of Granule Cell Progenitors..” The Journal of neuroscience : the official journal of the Society for Neuroscience 39.46 (2019): 9119–9129.

2018

Badura, Aleksandra, Jessica Verpeut, Julia Metzger, Talmo Pereira, Thomas Pisano, Ben Deverett, Dariya Bakshinskaya, and Samuel Wang. “Normal Cognitive and Social Development Require Posterior Cerebellar Activity.” Elife 7 (2018): n. pag.
Deverett, Ben, Sue Ann Koay, Marlies Oostland, and Samuel Wang. “Cerebellar Involvement in an Evidence-Accumulation Decision-Making Task.” Elife 7 (2018): n. pag.
Giovannucci, A, E Pnevmatikakis, B Deverett, T Pereira, J Fondriest, M Brady, S Wang, W Abbas, P Parés, and D Masip. “Automated Gesture Tracking in Head-Fixed Mice..” Journal of neuroscience methods 300 (2018): 184–195.
Marvin, Jonathan, Benjamin Scholl, Daniel Wilson, Kaspar Podgorski, Abbas Kazemipour, Johannes Müller, Susanne Schoch, Francisco Quiroz, Nelson Rebola, Huan Bao, Justin Little, Ariana Tkachuk, Edward Cai, Adam Hantman, Samuel S.-H. Wang, Victor DePiero, Bart Borghuis, Edwin Chapman, Dirk Dietrich, David DiGregorio, David Fitzpatrick, and Loren Looger. “Stability, Affinity, and Chromatic Variants of the Glutamate Sensor IGluSnFR..” Nature methods 15.11 (2018): 936–939.

2017

Giovannucci, Andrea, Aleksandra Badura, Ben Deverett, Farzaneh Najafi, Talmo Pereira, Zhenyu Gao, Ilker Ozden, Alexander Kloth, Eftychios Pnevmatikakis, Liam Paninski, Chris De Zeeuw, Javier Medina, and Samuel Wang. “Cerebellar Granule Cells Acquire a Widespread Predictive Feedback Signal During Motor Learning.” Nat Neurosci 20.5 (2017): 727–734.

2016

Cope, Elise, Brandy Briones, Adam Brockett, Susana Martinez, Pierre-Antoine Vigneron, Maya Opendak, Samuel Wang, and Elizabeth Gould. “Immature Neurons and Radial Glia, But Not Astrocytes or Microglia, Are Altered in Adult Cntnap2 and Shank3 Mice, Models of Autism.” eNeuro 3.5 (2016): n. pag.

2015

Kloth, Alexander, Aleksandra Badura, Amy Li, Adriana Cherskov, Sara Connolly, Andrea Giovannucci, Ali Bangash, Giorgio Grasselli, Olga Peñagarikano, Claire Piochon, Peter Tsai, Daniel Geschwind, Christian Hansel, Mustafa Sahin, Toru Takumi, Paul Worley, and Samuel Wang. “Cerebellar Associative Sensory Learning Defects in Five Mouse Autism Models.” Elife 4 (2015): e06085.

2014

Badura, Aleksandra, Xiaonan Richard Sun, Andrea Giovannucci, Laura Lynch, and Samuel Wang. “Fast Calcium Sensor Proteins for Monitoring Neural Activity.” Neurophotonics 1.2 (2014): 025008.
Najafi, Farzaneh, Andrea Giovannucci, Samuel Wang, and Javier Medina. “Coding of Stimulus Strength via Analog Calcium Signals in Purkinje Cell Dendrites of Awake Mice.” Elife 3 (2014): e03663.
Najafi, Farzaneh, Andrea Giovannucci, Samuel Wang, and Javier Medina. “Sensory-Driven Enhancement of Calcium Signals in Individual Purkinje Cell Dendrites of Awake Mice.” Cell Rep 6.5 (2014): 792–798.
Piochon, Claire, Alexander Kloth, Giorgio Grasselli, Heather Titley, Hisako Nakayama, Kouichi Hashimoto, Vivian Wan, Dana Simmons, Tahra Eissa, Jin Nakatani, Adriana Cherskov, Taisuke Miyazaki, Masahiko Watanabe, Toru Takumi, Masanobu Kano, Samuel Wang, and Christian Hansel. “Cerebellar Plasticity and Motor Learning Deficits in a Copy-Number Variation Mouse Model of Autism.” Nat Commun 5 (2014): 5586.
Schoenfeld, Timothy, Alexander Kloth, Brian Hsueh, Matthew Runkle, Gary Kane, Samuel Wang, and Elizabeth Gould. “Gap Junctions in the Ventral Hippocampal-Medial Prefrontal Pathway Are Involved in Anxiety Regulation.” J Neurosci 34.47 (2014): 15679–88.
Shi, Diana, Federico Trigo, Martin Semmelhack, and Samuel Wang. “Synthesis and Biological Evaluation of Bis-CNB-GABA, a Photoactivatable Neurotransmitter With Low Receptor Interference and Chemical Two-Photon Uncaging Properties.” J Am Chem Soc 136.5 (2014): 1976–81.
Wang, Samuel, Alexander Kloth, and Aleksandra Badura. “The Cerebellum, Sensitive Periods, and Autism.” Neuron 83.3 (2014): 518–32.

2013

Schneider, Eve, Eugene Civillico, and Samuel Wang. “Calcium-Based Dendritic Excitability and Its Regulation in the Deep Cerebellar Nuclei.” J Neurophysiol 109.9 (2013): 2282–92.
Sun, Xiaonan, Aleksandra Badura, Diego Pacheco, Laura Lynch, Eve Schneider, Matthew Taylor, Ian Hogue, Lynn Enquist, Mala Murthy, and Samuel Wang. “Fast GCaMPs for Improved Tracking of Neuronal Activity.” Nat Commun 4 (2013): 2170.

2012

Campbell, Benjamin, and Samuel Wang. “Familial Linkage Between Neuropsychiatric Disorders and Intellectual Interests.” PLoS One 7.1 (2012): e30405.
Kuhn, Bernd, Ilker Ozden, Yulia Lampi, Mazahir Hasan, and Samuel Wang. “An Amplified Promoter System for Targeted Expression of Calcium Indicator Proteins in the Cerebellar Cortex.” Front Neural Circuits 6 (2012): 49.
Ozden, Ilker, Daniel Dombeck, Tycho Hoogland, David Tank, and Samuel Wang. “Widespread State-Dependent Shifts in Cerebellar Activity in Locomoting Mice.” PLoS One 7.8 (2012): e42650.
Richard Sun, Andrea Giovannucci, Allyson Sgro, and Samuel Wang. “SnapShot: Optical Control and Imaging of Brain Activity.” Cell 149.7 (2012): 1650–1650.e2.

2010

Granstedt, Andrea, Bernd Kuhn, Samuel Wang, and Lynn Enquist. “Calcium Imaging of Neuronal Circuits in Vivo Using a Circuit-Tracing Pseudorabies Virus.” Cold Spring Harb Protoc 2010.4 (2010): pdb.prot5410.

2009

Granstedt, Andrea, Moriah Szpara, Bernd Kuhn, Samuel Wang, and Lynn Enquist. “Fluorescence-Based Monitoring of in Vivo Neural Activity Using a Circuit-Tracing Pseudorabies Virus.” PLoS One 4.9 (2009): e6923.
Hoogland, Tycho, Bernd Kuhn, Werner Göbel, Wenying Huang, Junichi Nakai, Fritjof Helmchen, Jane Flint, and Samuel Wang. “Radially Expanding Transglial Calcium Waves in the Intact Cerebellum.” Proc Natl Acad Sci U S A 106.9 (2009): 3496–501.
Ozden, Ilker, Megan Sullivan, Megan Lee, and Samuel Wang. “Reliable Coding Emerges from Coactivation of Climbing Fibers in Microbands of Cerebellar Purkinje Neurons.” J Neurosci 29.34 (2009): 10463–73.

2008

Ozden, Ilker, Megan Lee, Megan Sullivan, and Samuel Wang. “Identification and Clustering of Event Patterns from in Vivo Multiphoton Optical Recordings of Neuronal Ensembles.” J Neurophysiol 100.1 (2008): 495–503.
Sarkisov, Dmitry, and Samuel Wang. “Order-Dependent Coincidence Detection in Cerebellar Purkinje Neurons at the Inositol Trisphosphate Receptor.” J Neurosci 28.1 (2008): 133–42.
Wang, Samuel. “Functional Tradeoffs in Axonal Scaling: Implications for Brain Function.” Brain Behav Evol 72.2 (2008): 159–67.
Wang, Samuel, Jennifer Shultz, Mark Burish, Kimberly Harrison, Patrick Hof, Lex Towns, Matthew Wagers, and Krysta Wyatt. “Functional Trade-Offs in White Matter Axonal Scaling.” J Neurosci 28.15 (2008): 4047–56.

2007

O’Connor, Daniel, Gayle Wittenberg, and Samuel Wang. “Timing and Contributions of Pre-Synaptic and Post-Synaptic Parameter Changes During Unitary Plasticity Events at CA3-CA1 Synapses.” Synapse 61.8 (2007): 664–78.
Sarkisov, Dmitry, Shari Gelber, Jeffery Walker, and Samuel Wang. “Synapse Specificity of Calcium Release Probed by Chemical Two-Photon Uncaging of Inositol 1,4,5-Trisphosphate.” J Biol Chem 282.35 (2007): 25517–26.

2006

Sarkisov, Dmitry, and Samuel Wang. “Alignment and Calibration of a Focal Neurotransmitter Uncaging System.” Nat Protoc 1.2 (2006): 828–32.
Wittenberg, Gayle, and Samuel S.-H. Wang. “Malleability of Spike-Timing-Dependent Plasticity at the CA3-CA1 Synapse.” J Neurosci 26.24 (2006): 6610–7.

2005

O’Connor, Daniel, Gayle Wittenberg, and Samuel Wang. “Graded Bidirectional Synaptic Plasticity Is Composed of Switch-Like Unitary Events.” Proc Natl Acad Sci U S A 102.27 (2005): 9679–84.
O’Connor, Daniel, Gayle Wittenberg, and Samuel Wang. “Dissection of Bidirectional Synaptic Plasticity into Saturable Unidirectional Processes.” J Neurophysiol 94.2 (2005): 1565–73.
Shoham, Shy, Daniel O’Connor, Dmitry Sarkisov, and Samuel Wang. “Rapid Neurotransmitter Uncaging in Spatially Defined Patterns.” Nat Methods 2.11 (2005): 837–43.
Sullivan, Megan, Axel Nimmerjahn, Dmitry Sarkisov, Fritjof Helmchen, and Samuel Wang. “In Vivo Calcium Imaging of Circuit Activity in Cerebellar Cortex.” J Neurophysiol 94.2 (2005): 1636–44.
Wyatt, Krysta, Patima Tanapat, and Samuel Wang. “Speed Limits in the Cerebellum: Constraints from Myelinated and Unmyelinated Parallel Fibers.” Eur J Neurosci 21.8 (2005): 2285–90.

2004

Burish, Mark, Hao Yuan Kueh, and Samuel Wang. “Brain Architecture and Social Complexity in Modern and Ancient Birds.” Brain Behav Evol 63.2 (2004): 107–24.

2002

Harrison, Kimberly, Patrick Hof, and Samuel Wang. “Scaling Laws in the Mammalian Neocortex: Does Form Provide Clues to Function?.” J Neurocytol 31.3-5 (2002): 289–98. Print.

2001

Clark, Mitra, and Wang. “Scalable Architecture in Mammalian Brains.” Nature 411.6834 (2001): 189–93.